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c-FOS 抗体 (pThr232)

Name: c-FOS 抗体 (pThr232)
Brand: antibodies-online
SKU: ABIN7138813
Availability: OutOfStock

c-Fos 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts from COS7 cells (Lane 2), using FOS (Phospho-Thr232) Antibody. (c-FOS 抗体 (pThr232))

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FOS (Phospho-Thr232) antibody (left)or the same antibody preincubated with blocking peptide (right). (c-FOS 抗体 (pThr232))

IHC

2 images

产品编号 ABIN7138813

发货至: 中国

Datasheet as PDF

抗原 See all c-FOS (c-Fos) 抗体

c-FOS (c-Fos) (c-Fos)
抗原表位
26

25

25

23

18

16

15

15

10

9

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr232
适用
213

162

143

13

13

12

8

7

6

4

4

4

3

2

1
人
宿主
201

39

6

1
兔
Compatible Secondaries
克隆类型
204

42
多克隆
标记
107

13

11

9

7

6

6

6

6

6

6

6

6

6

6

6

4

4

4

4

4

4

4

2

2

2
This c-FOS antibody is un-conjugated
应用范围
202

80

80

76

39

35

35

25

14

13

11

6

5

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

交叉反应

人, 小鼠

纯化方法

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

免疫原

Peptide sequence around phosphorylation site of threonine 232(V-A-T(p)-P-E) derived from Human FOS .

亚型

IgG

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anti-c-Fos (c-Fos) (N-Term) antibody
c-Fos 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB:1:500-1:1000, IHC:1:50-1:100,

限制

仅限研究用
状态

Liquid

缓冲液

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

c-FOS (c-Fos) (c-Fos)

别名

FOS (c-Fos 产品)

别名

AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody

背景

Background:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

van Straaten F. Proc. Natl. Acad. Sci. U.S.A. 80:3183-3187(1983).
Hai T., Genes Dev. 3:2083-2090(1989).
Heilig R., Nature 421:601-607(2003).
Aliases: Activator protein 1 antibody, AP 1 antibody, C FOS antibody, Cellular oncogene c fos antibody, Cellular oncogene fos antibody, FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) antibody, FBJ murine osteosarcoma viral oncogene homolog antibody, FBJ murine osteosarcoma viral v fos oncogene homolog antibody, FBJ Osteosarcoma Virus antibody, FOS antibody, FOS protein antibody, FOS_HUMAN antibody, G0 G1 switch regulatory protein 7 antibody, G0/G1 switch regulatory protein 7 antibody, G0S7 antibody, Oncogene FOS antibody, p55 antibody, proto oncogene c Fos antibody, Proto oncogene protein c fos antibody, Proto-oncogene c-Fos antibody, v fos FBJ murine osteosarcoma viral oncogene homolog antibody

UniProt

P01100

途径

S100 Proteins