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- 抗原 See all MAP3K7 抗体
- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
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抗原表位
- pThr184
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAP3K7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of threonine 184 (I-Q-T(p)-H-M) derived from Human TAK1.
- 亚型
- IgG
- Top Product
- Discover our top product MAP3K7 Primary Antibody
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr187) antibody
MAP3K7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 300-470) antibodyMAP3K7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 1-579) antibodyMAP3K7 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 1-579) antibodyMAP3K7 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (Internal Region) antibodyVerified MAP3K7 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (Thr187) antibodyMAP3K7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 1-579) antibodyMAP3K7 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pSer412) antibodyMAP3K7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 471-579) antibodyMAP3K7 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3E8H4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 131-160), (N-Term) antibodyMAP3K7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34632 unconjugated
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
- 别名
- MAP3K7 (MAP3K7 产品)
- 别名
- si:ch211-225h9.1 antibody, zgc:110612 antibody, Tak1 antibody, MEKK7 antibody, TAK1 antibody, TGF1a antibody, B430101B05 antibody, C87327 antibody, mitogen-activated protein kinase kinase kinase 7 antibody, mitogen activated protein kinase kinase kinase 7 antibody, map3k7 antibody, Map3k7 antibody, MAP3K7 antibody
- 背景
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Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7.
Aliases: M3K7_HUMAN antibody, MAP3K 7 antibody, Map3k7 antibody, MEKK7 antibody, Mitogen activated protein kinase kinase kinase 7 antibody, Mitogen-activated protein kinase kinase kinase 7 antibody, TAK1 antibody, TGF beta activated kinase 1 antibody, TGF-beta-activated kinase 1 antibody, TGF1a antibody, Transforming growth factor beta activated kinase 1 antibody, Transforming growth factor-beta-activated kinase 1 antibody
- UniProt
- O43318
- 途径
- NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway
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