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alpha Adducin 抗体 (pSer726)

ADD1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138686
发货至: 中国
  • 抗原 See all alpha Adducin (ADD1) 抗体
    alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
    抗原表位
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    pSer726
    适用
    • 91
    • 56
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    宿主
    • 90
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    克隆类型
    • 89
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    多克隆
    标记
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    This alpha Adducin antibody is un-conjugated
    应用范围
    • 59
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of serine 726 (T-P-S(p)-F-L) derived from Human ADD1.
    亚型
    IgG
    Top Product
    Discover our top product ADD1 Primary Antibody
  • 应用备注
    WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
    别名
    ADD1 (ADD1 产品)
    别名
    ADDA antibody, AI256389 antibody, alpha-adducin antibody, bZ1H20.1 antibody, cb787 antibody, zgc:158352 antibody, add2 antibody, adda antibody, add1-a antibody, ADD1 antibody, adducin 1 antibody, adducin 1 (alpha) antibody, adducin 1 S homeolog antibody, ADD1 antibody, Add1 antibody, add1 antibody, add1.S antibody
    背景

    Background: Adducins are a family of cytoskeleton proteins encoded by three genes (a, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. a- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. a- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.

    Pariser H, et al. Proc Natl Acad Sci USA 2005 Aug 30, 102(35): 12407-12
    Tamaru S, et al. Biochem Biophys Res Commun 2005 Jul 01, 332(2): 347-51
    Barkalow KL, et al. J Cell Biol 2003 May 12, 161(3): 557-70

    Aliases: ADD A antibody, ADD1 antibody, ADDA antibody, ADDA_HUMAN antibody, Adducin 1 (alpha) antibody, Alpha adducin antibody, Alpha-adducin antibody, Erythrocyte adducin alpha subunit antibody, Erythrocyte adducin subunit alpha antibody, MGC3339 antibody, MGC44427 antibody, OTTHUMP00000151163 antibody, OTTHUMP00000151164 antibody, OTTHUMP00000151165 antibody, OTTHUMP00000218664 antibody, OTTHUMP00000218665 antibody

    UniProt
    P35611
    途径
    Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
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