BIM 抗体 (pSer69)
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- 抗原 See all BIM (BCL2L11) 抗体
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
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抗原表位
- pSer69
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BIM antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of serine 69 (P-A-S(p)-P-G) derived from Human BIM.
- 亚型
- IgG
- Top Product
- Discover our top product BCL2L11 Primary Antibody
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- 应用备注
- IHC:1:50-1:100, IF:1:100-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
- 别名
- BCL2L11 (BCL2L11 产品)
- 别名
- bim antibody, BAM antibody, BIM antibody, BOD antibody, 1500006F24Rik antibody, Bim antibody, Bod antibody, BimL antibody, BIMEL antibody, BCL2-like 11 antibody, BCL2 like 11 antibody, BCL2-like 11 (apoptosis facilitator) antibody, bcl2l11 antibody, BCL2L11 antibody, Bcl2l11 antibody
- 背景
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Background: Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-a1, isoform Bim-a2 and isoform Bim-a3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis
Fukazawa H, et al. (2004) Mol Cancer Ther , 3(10): 1281-1288
Luciano F, et al. (2003) Oncogene , 22(43): 6785-6793Aliases: BCL2 like 11 antibody, B2L11_HUMAN antibody, BAM antibody, Bcl 2 interacting protein Bim antibody, Bcl 2 related ovarian death agonist antibody, Bcl-2-like protein 11 antibody, BCL2 interacting mediator of cell death antibody, BCL2 like 11 (apoptosis facilitator) antibody, BCL2 like protein 11 antibody, Bcl2-interacting mediator of cell death antibody, Bcl2-L-11 antibody, Bcl2l11 antibody, BIM alpha6 antibody, BIM antibody, BIM beta6 antibody, BIM beta7 antibody, BimEL antibody, BimL antibody, BOD antibody
- UniProt
- O43521
- 途径
- PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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