PKC delta 抗体 (pSer645)
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- 抗原 See all PKC delta (PKCd) 抗体
- PKC delta (PKCd) (Protein Kinase C, delta (PKCd))
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抗原表位
- pSer645
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PKC delta antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of serine 645 (R-L-S(p)-Y-S) derived from Human PKCd.
- 亚型
- IgG
- Top Product
- Discover our top product PKCd Primary Antibody
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- 应用备注
- WB:1:500-1:1000, IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PKC delta (PKCd) (Protein Kinase C, delta (PKCd))
- 别名
- PRKCD (PKCd 产品)
- 别名
- MAY1 antibody, PKCD antibody, nPKC-delta antibody, AI385711 antibody, D14Ertd420e antibody, PKC[d] antibody, PKCdelta antibody, Pkcd antibody, fb09d10 antibody, fv43b11 antibody, prkcd antibody, wu:fb09d10 antibody, wu:fv43b11 antibody, zgc:56558 antibody, PKC-delta antibody, may1 antibody, npkc-delta antibody, pkc-delta2 antibody, pkcd antibody, tpa-1 antibody, protein kinase C delta antibody, protein kinase C, delta antibody, protein kinase C, delta a antibody, protein kinase C delta L homeolog antibody, PRKCD antibody, Prkcd antibody, prkcda antibody, prkcd.L antibody, prkcd antibody
- 背景
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Background: This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
Kei Sakamoto, et,al. (2003) Am J Physiol Endocrinol Metab , 285: E1081 - E1088.
Ling Zhang, et,al. (2004) J. Biol. Chem , 279: 28315 - 28319.
Kristof Van Kolen et,al. (2006) FEBS J , 273: 1843 - 1854.
Martin Villalba, et,al. (2002) J. Cell Biol , 157: 253.Aliases: CVID9 antibody, D14Ertd420e antibody, Kinase PKC delta antibody, KPCD antibody, KPCD_HUMAN antibody, MAY 1 antibody, MAY1 antibody, MGC49908 antibody, nPKC delta antibody, nPKC-delta antibody, PCKd antibody, PKC d antibody, PKC delta antibody, PKCD antibody, PKCdelta antibody, PRKC D antibody, PRKC delta antibody, Prkcd antibody, Protein Kinase C delta antibody, Protein kinase C delta type antibody, Protein kinase C delta VIII antibody, Protein Kinase Cdelta antibody, Tyrosine protein kinase PRKCD antibody
- UniProt
- Q05655
- 途径
- Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism
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