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BRCA2 抗体 (pSer3291)

Name: BRCA2 抗体 (pSer3291)
Brand: antibodies-online
SKU: ABIN7138558
Availability: OutOfStock

BRCA2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts from 293 cells using BRCA2 (Phospho-Ser3291) Antibody. (BRCA2 抗体 (pSer3291))

1 image

产品编号 ABIN7138558

发货至: 中国

Datasheet as PDF

抗原 See all BRCA2 抗体

BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
抗原表位
11

7

5

4

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer3291
适用
42

23

20

4

2

1

1

1
人
宿主
41

7
兔
Compatible Secondaries
克隆类型
40

8
多克隆
标记
31

3

2

2

2

2

2

2

1

1
This BRCA2 antibody is un-conjugated
应用范围
23

14

9

6

5

4

3

3

2

1

1

1

1
Western Blotting (WB), ELISA

交叉反应

人, 小鼠, 大鼠

纯化方法

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

免疫原

Peptide sequence around phosphorylation site of Serine 3291 (F-V-S(p)-P-A) derived from Human BRCA2.

亚型

IgG

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anti-Breast Cancer 2, Early Onset (BRCA2) (AA 251-495) antibody
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应用备注

WB:1:500-1:1000,

限制

仅限研究用
状态

Liquid

缓冲液

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

BRCA2 (Breast Cancer 2, Early Onset (BRCA2))

别名

BRCA2 (BRCA2 产品)

别名

BRCC2 antibody, BROVCA2 antibody, FACD antibody, FAD antibody, FAD1 antibody, FANCB antibody, FANCD antibody, FANCD1 antibody, GLM3 antibody, PNCA2 antibody, 30169 antibody, BcDNA:SD25109 antibody, CG13583 antibody, CG13584 antibody, CG30169 antibody, Dmel\\CG30169 antibody, brca2 antibody, dmbrca2 antibody, fancd1 antibody, BRCA2 antibody, brcc2 antibody, brovca2 antibody, facd antibody, fad antibody, fad1 antibody, fancb antibody, AI256696 antibody, AW045498 antibody, Fancd1 antibody, RAB163 antibody, BRCA2, DNA repair associated antibody, Breast cancer 2, early onset homolog antibody, breast cancer 2, early onset antibody, BRCA2 antibody, Brca2 antibody, brca2 antibody, LOC584780 antibody

背景

Background:
Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures.

Wooster R., Nature 378:789-792(1995).
Tavtigian S.V., Nat. Genet. 12:333-337(1996).
Dunham A., Nature 428:522-528(2004).
Aliases: BRCA 2 antibody, BRCA1/BRCA2 containing complex subunit 2 antibody, Brca2 antibody, BRCA2, DNA repair associated antibody, BRCA2_HUMAN antibody, BRCC 2 antibody, BRCC2 antibody, Breast and ovarian cancer susceptibility gene early onset antibody, breast and ovarian cancer susceptibility protein 2 antibody, Breast cancer 2 early onset antibody, Breast Cancer 2 tumor suppressor antibody, Breast cancer susceptibility protein BRCA2 antibody, Breast cancer type 2 susceptibility protein antibody, BROVCA2 antibody, FACD antibody, FAD 1 antibody, FAD antibody, FAD1 antibody, FANCB antibody, FANCD 1 antibody, FANCD antibody, FANCD1 antibody, FANCD1 gene antibody, Fanconi anemia complementation group D1 antibody, Fanconi anemia group D1 protein antibody, GLM3 antibody, mutant BRCA2 antibody, OTTHUMP00000018803 antibody, OTTHUMP00000042401 antibody, PNCA2 antibody, XRCC11 antibody

UniProt

P51587

途径

DNA Damage Repair, M Phase, Maintenance of Protein Location