FBXL3 抗体 (pSer320)
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- 抗原 See all FBXL3 抗体
- FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))
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抗原表位
- pSer320
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FBXL3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of serine 320 (S-V-S(p)-K-D) derived from Human FBXL3.
- 亚型
- IgG
- Top Product
- Discover our top product FBXL3 Primary Antibody
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- 应用备注
- WB:1:500-1:1000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))
- 别名
- FBXL3 (FBXL3 产品)
- 别名
- FBL3 antibody, FBL3A antibody, FBXL3A antibody, AU041772 antibody, AW212966 antibody, FBK antibody, Fbl3a antibody, Fbxl3a antibody, Ovtm antibody, Play68 antibody, fbxl3 antibody, FBXL3 antibody, F7A7.240 antibody, F7A7_240 antibody, im:7153024 antibody, zgc:103721 antibody, F-box and leucine rich repeat protein 3 antibody, F-box and leucine-rich repeat protein 3 antibody, F-box and leucine-rich repeat protein 3 L homeolog antibody, RNI-like superfamily protein antibody, F-box and leucine-rich repeat protein 3a antibody, FBXL3 antibody, Fbxl3 antibody, fbxl3.L antibody, fbxl3 antibody, AT5G01720 antibody, fbxl3a antibody
- 背景
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Background:
Substrate-recognition component of the SCF(FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF(FBXL3) complex is counteracted by the SCF(FBXL21) complex.
1)Busino L., Bassermann F., Maiolica A., Lee C., Nolan P.M., Godinho S.I., Draetta G.F., Pagano M. Science 316:900-904(2007)2)Yoo S.H., Mohawk J.A., Siepka S.M., Shan Y., Huh S.K., Hong H.K., Kornblum I., Kumar V., Koike N., Xu M., Nussbaum J., Liu X., Chen Z., Chen Z.J., Green C.B., Takahashi J.S.Cell 152:1091-1105(2013)Aliases: F box and leucine rich repeat protein 3 antibody; F box and leucine rich repeat protein 3A antibody; F box protein Fbl3a antibody; F-box and leucine-rich repeat protein 3A antibody; F-box/LRR-repeat protein 3 antibody; F-box/LRR-repeat protein 3A antibody; FBL3 antibody; FBL3A antibody; Fbxl3 antibody; FBXL3_HUMAN antibody; FBXL3A antibody
- UniProt
- Q9UKT7
- 途径
- Photoperiodism
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