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FOXO4 抗体 (pSer197)

FOXO4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138463
发货至: 中国
  • 抗原 See all FOXO4 抗体
    FOXO4 (Forkhead Box O4 (FOXO4))
    抗原表位
    • 26
    • 18
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    pSer197
    适用
    • 135
    • 70
    • 62
    • 10
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
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    宿主
    • 133
    • 1
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    克隆类型
    • 123
    • 12
    多克隆
    标记
    • 64
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    This FOXO4 antibody is un-conjugated
    应用范围
    • 104
    • 50
    • 39
    • 39
    • 24
    • 16
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    • 9
    • 7
    • 2
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of serine 197 (A-A-S(p)-M-D) derived from Human AFX.
    亚型
    IgG
    Top Product
    Discover our top product FOXO4 Primary Antibody
  • 应用备注
    WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    FOXO4 (Forkhead Box O4 (FOXO4))
    别名
    FOXO4 (FOXO4 产品)
    背景

    Background: Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.

    Di Maira G, et al. (2005)Cell Death Differ, 12(6): 668-77.
    Essers MA, et al. EMBO J 2004 Nov. 11.
    Brownawell AM, (2001) Mol Cell Biol, 21(10): 3534-46.
    Kops GJ, et al. (1999) Nature, 398(6728): 630-4.

    Aliases: AFX antibody, AFX1 antibody, Afxh antibody, ALL1-fused gene from X chromosome antibody, Fork head domain transcription factor AFX1 antibody, Forkhead box O4 antibody, Forkhead box protein O4 antibody, FOXO 4 antibody, Foxo4 antibody, FOXO4_HUMAN antibody, MGC117660 antibody, MGC120490 antibody, Mixed lineage leukemia, translocated to, 7 antibody, MLLT7 antibody, Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog, Drosophila), translocated to, 7 antibody, Myeloid/lymphoid or mixed lineage leukemia, translocated to, 7 antibody, RGD1561201 antibody

    UniProt
    P98177
    途径
    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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