IGFBP3 抗体 (pSer183)
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- 抗原 See all IGFBP3 抗体
- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
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抗原表位
- pSer183
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IGFBP3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of serine 183(K-D-S(p)-Q-R) derived from Human IGFBP-3 .
- 亚型
- IgG
- Top Product
- Discover our top product IGFBP3 Primary Antibody
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- 应用备注
- WB:1:500-1:1000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
- 别名
- IGFBP3 (IGFBP3 产品)
- 背景
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Background:
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Zhang Q, Steinle JJ (2013)Invest Ophthalmol Vis Sci 54, 3052-7 . Cobb LJ, Liu B, Lee KW, Cohen P (2006) Cancer Res 66, 10878-84 .Aliases: Acid stable subunit of the 140 K IGF complex antibody, Binding protein 29 antibody, Binding protein 53 antibody, BP 53 antibody, BP53 antibody, Growth hormone dependent binding protein antibody, IBP 3 antibody, IBP-3 antibody, IBP3 antibody, IBP3_HUMAN antibody, IGF binding protein 3 antibody, IGF-binding protein 3 antibody, IGFBP 3 antibody, IGFBP-3 antibody, IGFBP3 antibody, Insulin Like Growth Factor Binding Protein 3 antibody, Insulin-like growth factor binding protein 3 precursor antibody, Insulin-like growth factor-binding protein 3 antibody
- UniProt
- P17936
- 途径
- Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
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