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BAD 抗体 (pSer155)

BAD 适用: 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138438
发货至: 中国
  • 抗原 See all BAD 抗体
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    抗原表位
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    pSer155
    适用
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    小鼠
    宿主
    • 440
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    克隆类型
    • 430
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    多克隆
    标记
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    This BAD antibody is un-conjugated
    应用范围
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    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of serine 155(R-M-S(p)-D-E) derived from Human BAD.
    亚型
    IgG
    Top Product
    Discover our top product BAD Primary Antibody
  • 应用备注
    WB:1:500-1:1000, IHC:1:50-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    别名
    Bad (BAD 产品)
    别名
    bad antibody, fa01b12 antibody, wu:fa01b12 antibody, wu:fa96d04 antibody, BAD antibody, BBC2 antibody, BCL2L8 antibody, AI325008 antibody, Bbc2 antibody, BCL2-associated agonist of cell death b antibody, BCL2 associated agonist of cell death antibody, BCL2-associated agonist of cell death antibody, badb antibody, BAD antibody, Bad antibody
    背景

    Background:

     Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

    Schurmann A., Mooney A.F., Sanders L.C., Sells M.A., Wang H.G., Reed J.C., Bokoch G.M.Mol. Cell. Biol. 20:453-461(2000)
    Jakobi R., Moertl E., Koeppel M.A.J. Biol. Chem. 276:16624-16634(2001)        

    Aliases: Bad antibody; Bbc6Bcl2-associated agonist of cell death antibody; BAD antibody; Bcl-2-binding component 6 antibody; Bcl-xL/Bcl-2-associated death promoter antibody; Bcl2 antagonist of cell death antibody

    UniProt
    Q61337
    途径
    MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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