CDC25B 抗体 (pSer149)
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- 抗原 See all CDC25B 抗体
- CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
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抗原表位
- pSer149
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC25B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 小鼠, 大鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 免疫原
- Peptide sequence around phosphorylation site of Serine 149 (F-R-S(p)-L-P) derived from Mouse Cdc25B.
- 亚型
- IgG
- Top Product
- Discover our top product CDC25B Primary Antibody
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- 应用备注
- WB:1:500-1:1000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
- 别名
- Cdc25b (CDC25B 产品)
- 背景
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Background:
Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
Li G, et al. (2010) Retrovirology.7:59.
Wang Z,et al. (2010) BMC Cancer.10:233.
Lucci MA,et al. (2010) Cell Oncol.32(5-6):361-72.Aliases: CDC25B
- UniProt
- Q9DBN8
- 途径
- Cell Division Cycle, M Phase, Autophagy
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