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- 抗原 See all EIF4G1 抗体
- EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))
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抗原表位
- pSer1232
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EIF4G1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of serine 1232 (P-V-S(p)-P-L) derived from Human eIF4G.
- 亚型
- IgG
- Top Product
- Discover our top product EIF4G1 Primary Antibody
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anti-Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) (AA 1500-1599) antibody
EIF4G1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A9 unconjugated
anti-Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) antibodyEIF4G1 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) (AA 1500-1599) antibodyEIF4G1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A10 unconjugated
anti-Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) antibodyEIF4G1 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) (AA 1-645) antibodyEIF4G1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) (AA 400-500) antibodyEIF4G1 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) (Ser1232) antibodyEIF4G1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) (AA 1500-1599) antibodyEIF4G1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) (AA 539-588) antibodyEIF4G1 适用: 人, 小鼠, 大鼠, Cow, 猴, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) (AA 400-500) antibodyEIF4G1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB:1:500-1:1000, IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))
- 别名
- EIF4G1 (EIF4G1 产品)
- 别名
- EIF4GI antibody, CG10811 antibody, Dmel\\CG10811 antibody, EIF4G antibody, Eif4G antibody, deIF4G antibody, eIF-4G antibody, eIF4g antibody, p200 antibody, EIF4G1 antibody, wu:fb50a05 antibody, wu:fc60b06 antibody, eif4g antibody, CUCUMOVIRUS MULTIPLICATION 2 antibody, CUM2 antibody, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G antibody, eukaryotic translation initiation factor 4G antibody, DDBDRAFT_0217646 antibody, DDBDRAFT_0217647 antibody, DDBDRAFT_0234257 antibody, DDB_0217646 antibody, DDB_0217647 antibody, DDB_0234257 antibody, NV18824 antibody, EIF-4G1 antibody, EIF4F antibody, P220 antibody, PARK18 antibody, p220 antibody, E030015G23Rik antibody, eIF4GI antibody, eukaryotic translation initiation factor 4 gamma 1 antibody, eukaryotic translation initiation factor 4G antibody, eukaryotic translation initiation factor 4 gamma, 1a antibody, eukaryotic translation initiation factor 4 gamma, 1 S homeolog antibody, eukaryotic initiation factor antibody, eukaryotic translation initiation factor 4 gamma antibody, eukaryotic translation initiation factor 4 gamma, 1 antibody, eukaryotic translation initiation factor 4, gamma 1 antibody, EIF4G1 antibody, eIF4G antibody, eif4g1a antibody, LOC704923 antibody, eif4g1.S antibody, EIF4G antibody, eIF4g antibody, Eif4g antibody, Eif4g1 antibody
- 背景
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Background: eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. Interacts with eIF3, mutually exclusive with EIF4A1 or EIFA2, EIF4E and through its N-terminus with PAPBC1. Interacts through its C-terminus with the serine/threonine kinases MKNK1, and with MKNK2. Appears to act as a scaffold protein, holding these enzymes in place to phosphorylate EIF4E. Non-phosphorylated EIF4EBP1 competes with EIF4G1/EIF4G3 to interact with EIF4E, insulin stimulated MAP-kinase (MAPK1 and MAPK3) phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. EIF4G1/EIF4G3 interacts with PABPC1 to bring about circularization of the mRNA. Rapamycin can attenuate insulin stimulation mediated by FKBPs. Interacts with EIF4E3. Interacts with MIF4GD. Interacts with rotavirus A NSP3, in this interaction, NSP3 takes the place of PABPC1 thereby inducing shutoff of host protein synthesis
De Gregorio, E. et al. (1998) RNA 4, 828-836.
Ohlmann, T. et al. (1996) EMBO J. 15, 1371-1382.
Borman, A.M. and Kean, K.M. (1997) Virology 237, 129-136.
Gradi, A. et al. (1998) Mol Cell Biol 18, 334-42.Aliases: DKFZp686A1451 antibody, eIF 4 gamma 1 antibody, eIF 4G 1 antibody, eIF 4G1 antibody, eIF-4-gamma 1 antibody, eIF-4G 1 antibody, eIF-4G1 antibody, EIF4 gamma antibody, EIF4F antibody, EIF4G antibody, EIF4G1 antibody, EIF4GI antibody, Eukaryotic translation initiation factor 4 gamma 1 antibody, IF4G1_HUMAN antibody, p220 antibody
- UniProt
- Q04637
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