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- 抗原 See all Synaptoporin (SYNPR) 抗体
- Synaptoporin (SYNPR)
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Synaptoporin antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 小鼠, 大鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 免疫原
- Peptide sequence around aa.257~261(G-P-T-S-F)derived from Rat synaptophysin 2.
- 亚型
- IgG
- Top Product
- Discover our top product SYNPR Primary Antibody
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anti-Synaptoporin (SYNPR) (AA 199-265) antibody
SYNPR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (C-Term) antibodySYNPR 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) antibodySYNPR 适用: 大鼠, 小鼠, Hamster WB, ICC, IP 宿主: 豚鼠 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (AA 31-130) antibodySYNPR 适用: 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (AA 91-140) antibodySYNPR 适用: 人, 大鼠, 小鼠, 豚鼠, 马, 兔, 斑马鱼, Cow, 犬, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (Middle Region) antibodySYNPR 适用: 人, 大鼠, 小鼠, 豚鼠, 马, 兔, 斑马鱼, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB:1:500-1:1000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Synaptoporin (SYNPR)
- 别名
- Synpr (SYNPR 产品)
- 别名
- si:ch211-263a23.1 antibody, si:zc263a23.1 antibody, wu:fq14d10 antibody, SYNPR antibody, MGC139775 antibody, MGC147520 antibody, DKFZp459F1433 antibody, SPO antibody, 1500003F20Rik antibody, synaptoporin antibody, synpr antibody, SYNPR antibody, Synpr antibody
- 背景
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Background:
Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4).
Wiedenmann, B. et al. (1986) Proc Natl Acad Sci USA 83, 3500-4.
Valtorta, F. et al. (2004) Bioessays 26, 445-53.
Arthur, C.P. and Stowell, M.H. (2007) Structure 15, 707-14.
Bonanomi, D. et al. (2007) Biochem J 404, 525-34.Aliases: Synpr antibody, Synaptoporin antibody
- UniProt
- P22831
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