HSPG2 抗体 (AA 3601-3700)
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- 抗原 See all HSPG2 抗体
- HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))
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抗原表位
- AA 3601-3700
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSPG2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Cow,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Heparan Sulfate Proteoglycan 2
- 亚型
- IgG
- Top Product
- Discover our top product HSPG2 Primary Antibody
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- 应用备注
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))
- 别名
- Heparan Sulfate Proteoglycan 2 (HSPG2 产品)
- 别名
- HSPG antibody, PLC antibody, PRCAN antibody, SJA antibody, SJS antibody, SJS1 antibody, HSPG2 antibody, AI852380 antibody, Pcn antibody, Plc antibody, per antibody, Per antibody, heparan sulfate proteoglycan 2 antibody, perlecan (heparan sulfate proteoglycan 2) antibody, HSPG2 antibody, hspg2 antibody, Hspg2 antibody
- 背景
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Synonyms: Perlecan, Basement membrane specic heparan sulfate proteoglycan core protein, Endorepellin domain V region, Heparan Sulfate Proteoglycan, Heparan sulfate proteoglycan of basement membrane, HSPG 2, HSPG, Hspg2, LG3 peptide, Perlecan, PLC antibody Schwartz Jampel syndrome 1 chondrodystrophic myotonia, SJA antibody SJS antibody SJS1 antibody.
Background: This gene encodes the perlecan protein, which consists of a core protein to which three long chains of glycosaminoglycans(heparan sulfate or chondroitin sulfate) are attached. The perlecan protein is a large multidomain proteoglycan that binds to and cross-links many extracellular matrix components and cell-surface molecules. It has been shown that this protein interacts with laminin, prolargin, collagen type IV, FGFBP1, FBLN2, FGF7 and Transthyretin, etc. and plays essential roles in multiple biological activities. Perlecan is a key component of the vascular extracellular matrix, where it helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. It can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation. It is a major component of basement membranes, where it is involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. Mutations in this gene cause Schwartz-Jampel syndrome type 1, Silverman-Handmaker type of dyssegmental dysplasia, and Tardive dyskinesia.[provided by RefSeq, Mar 2010].
- 基因ID
- 117194
- 途径
- Glycosaminoglycan Metabolic Process, Lipid Metabolism
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