PRCP 抗体
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- 抗原 See all PRCP 抗体
- PRCP (Prolylcarboxypeptidase (PRCP))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRCP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen affinity purification
- 免疫原
- Fusion protein of Human PRCP
- 亚型
- IgG
- Top Product
- Discover our top product PRCP Primary Antibody
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- 应用备注
- ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PRCP (Prolylcarboxypeptidase (PRCP))
- 别名
- PRCP (PRCP 产品)
- 别名
- OI13 antibody, PCOLC antibody, PCP antibody, PCP2 antibody, TLD antibody, humpcp antibody, MGC145178 antibody, 2510048K03Rik antibody, 2610104A14Rik antibody, AI451719 antibody, HUMPCP antibody, zgc:91816 antibody, bone morphogenetic protein 1 antibody, prolylcarboxypeptidase antibody, lysosomal Pro-X carboxypeptidase antibody, prolylcarboxypeptidase (angiotensinase C) antibody, BMP1 antibody, prcp antibody, LOC5579822 antibody, CpipJ_CPIJ006123 antibody, CpipJ_CPIJ006124 antibody, Prcp antibody, PRCP antibody
- 背景
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Background: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH , but the enzyme activity is retained with some substrates at neutral pH . This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Aliases: Angiotensinase C antibody, HUMPCP antibody, Lysosomal carboxypeptidase C antibody, Lysosomal Pro X carboxypeptidase antibody, Lysosomal Pro-X carboxypeptidase antibody, MGC2202 antibody, PCP antibody, PCP_HUMAN antibody, PRCP antibody, Proline carboxypeptidase antibody, Prolylcarboxypeptidase (angiotensinase C) antibody, Prolylcarboxypeptidase antibody, prolylcarboxypeptidase isoform 1 preproprotein antibody
- UniProt
- P42785
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