PCP4 抗体
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- 抗原 See all PCP4 抗体
- PCP4 (Purkinje Cell Protein 4 (PCP4))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCP4 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Antigen affinity purification
- 免疫原
- Fusion protein of Human PCP4
- 亚型
- IgG
- Top Product
- Discover our top product PCP4 Primary Antibody
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- 应用备注
- ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:5-1:20,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PCP4 (Purkinje Cell Protein 4 (PCP4))
- 别名
- PCP4 (PCP4 产品)
- 别名
- PEP-19 antibody, P16Rimb19 antibody, Pcp-4 antibody, Pep19 antibody, PEPZ19 antibody, pep-19 antibody, Purkinje cell protein 4 antibody, PCP4 antibody, Pcp4 antibody
- 背景
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Background: PCP-4 (Purkinje cell protein 4), also known as PEP-19, is a calmodulin (CaM) regulatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer's disease and Huntington's disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome.
Aliases: Brain specific antigen PCP 4 antibody, Brain specific polypeptide PEP 19 antibody, Brain specific polypeptide PEP19 antibody, Brain-specific antigen PCP-4 antibody, Brain-specific polypeptide PEP-19 antibody, OTTHUMP00000109191 antibody, Pcp4 antibody, PCP4_HUMAN antibody, PEP19 antibody, Purkinje cell protein 4 antibody
- UniProt
- P48539
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