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Recombinant PTBP1 抗体

PTBP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 8A1 unconjugated Recombinant Antibody
产品编号 ABIN7127781
发货至: 中国
  • 抗原 See all PTBP1 抗体
    PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
    抗体类型
    Recombinant Antibody
    适用
    • 52
    • 18
    • 16
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
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    宿主
    • 45
    • 6
    • 1
    克隆类型
    • 35
    • 17
    单克隆
    标记
    • 30
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
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    This PTBP1 antibody is un-conjugated
    应用范围
    • 34
    • 19
    • 13
    • 9
    • 7
    • 3
    • 2
    • 1
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    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human PTBP1
    克隆位点
    8A1
    亚型
    IgG
    Top Product
    Discover our top product PTBP1 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
    别名
    PTBP1 (PTBP1 产品)
    背景

    Background: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).

    Aliases: Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I), PTBP1, PTB

    UniProt
    P26599
    途径
    Regulation of Muscle Cell Differentiation
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