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Recombinant MLKL 抗体 (pSer358)

MLKL 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 4A6 unconjugated Recombinant Antibody
产品编号 ABIN7127713
发货至: 中国
  • 抗原 See all MLKL 抗体
    MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
    抗体类型
    Recombinant Antibody
    抗原表位
    • 11
    • 10
    • 10
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer358
    适用
    • 55
    • 40
    • 17
    • 1
    • 1
    宿主
    • 67
    • 7
    克隆类型
    • 61
    • 13
    单克隆
    标记
    • 32
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    This MLKL antibody is un-conjugated
    应用范围
    • 33
    • 28
    • 13
    • 11
    • 6
    • 5
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human Phospho-MLKL (S358)
    克隆位点
    4A6
    亚型
    IgG
    Top Product
    Discover our top product MLKL Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
    别名
    MLKL (MLKL 产品)
    别名
    MLKL antibody, 9130019I15Rik antibody, mixed lineage kinase domain like pseudokinase antibody, mixed lineage kinase domain-like antibody, MLKL antibody, mlkl antibody, Mlkl antibody
    背景

    Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

    Aliases: Mixed lineage kinase domain-like protein, hMLKL, MLKL

    UniProt
    Q8NB16
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