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Recombinant LAT 抗体 (pTyr191)

LAT 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Monoclonal 2E4 unconjugated Recombinant Antibody
产品编号 ABIN7127705
发货至: 中国
  • 抗原 See all LAT 抗体
    LAT (Linker For Activation of T Cells (LAT))
    抗体类型
    Recombinant Antibody
    抗原表位
    • 18
    • 15
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    pTyr191
    适用
    • 119
    • 56
    • 40
    • 1
    宿主
    • 112
    • 7
    • 2
    • 1
    克隆类型
    • 116
    • 6
    单克隆
    标记
    • 57
    • 7
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    This LAT antibody is un-conjugated
    应用范围
    • 67
    • 39
    • 39
    • 39
    • 15
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    • 4
    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human Phospho-LAT (Y191)
    克隆位点
    2E4
    亚型
    IgG
    Top Product
    Discover our top product LAT Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    LAT (Linker For Activation of T Cells (LAT))
    别名
    LAT (LAT 产品)
    别名
    LAT antibody, lat antibody, LAT1 antibody, pp36 antibody, linker for activation of T-cells antibody, linker for activation of T cells antibody, LAT antibody, lat antibody, Lat antibody
    背景

    Background: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

    Aliases: Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38, LAT

    UniProt
    O43561
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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