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Recombinant ERN1 抗体 (pSer724)

ERN1 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 1F12 unconjugated Recombinant Antibody
产品编号 ABIN7127692
发货至: 中国
  • 抗原 See all ERN1 抗体
    ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
    抗体类型
    Recombinant Antibody
    抗原表位
    • 16
    • 16
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer724
    适用
    • 71
    • 51
    • 45
    • 16
    • 1
    宿主
    • 69
    • 5
    • 3
    • 1
    克隆类型
    • 71
    • 7
    单克隆
    标记
    • 34
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ERN1 antibody is un-conjugated
    应用范围
    • 73
    • 37
    • 30
    • 26
    • 26
    • 10
    • 10
    • 9
    • 9
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human Phospho-ERN1 (S724)
    克隆位点
    1F12
    亚型
    IgG
    Top Product
    Discover our top product ERN1 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
    别名
    ERN1 (ERN1 产品)
    背景

    Background: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation (PubMed:9637683, PubMed:11175748, PubMed:12637535). The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis (PubMed:24508390).

    Aliases: Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, hIRE1p, Ire1-alpha, IRE1a, Serine/threonine-protein kinase, Endoribonuclease, ERN1

    UniProt
    O75460
    途径
    ER-Nucleus Signaling, Unfolded Protein Response
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