Recombinant PELP1 抗体
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- 抗原 See all PELP1 抗体
- PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))
- 抗体类型
- Recombinant Antibody
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This PELP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Affinity-chromatography
- 免疫原
- A synthesized peptide derived from human PELP1
- 克隆位点
- 6H4
- 亚型
- IgG
- Top Product
- Discover our top product PELP1 Primary Antibody
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anti-Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) (AA 1021-1180) antibody
PELP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) (AA 1031-1180) antibodyPELP1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F1D1 unconjugated
anti-Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) (AA 1031-1180) antibodyPELP1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2D6D11 unconjugated
anti-Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) antibodyPELP1 适用: 小鼠, 人, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) (AA 744-771) antibodyPELP1 适用: 小鼠, 人 WB, IHC (p) 宿主: 兔 Polyclonal RB17558 unconjugated
anti-Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) (AA 337-410) antibodyPELP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F7 unconjugated
anti-Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) (Internal Region) antibodyPELP1 适用: 小鼠, 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) antibodyPELP1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) (AA 337-410) antibodyPELP1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4F3 unconjugated
anti-Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1) (AA 791-840) antibodyPELP1 适用: 小鼠, 人, 大鼠, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))
- 别名
- PELP1 (PELP1 产品)
- 别名
- MNAR antibody, P160 antibody, RGD1306320 antibody, 4930563C04Rik antibody, proline, glutamate and leucine rich protein 1 antibody, proline, glutamate and leucine rich protein 1 L homeolog antibody, proline, glutamic acid and leucine rich protein 1 antibody, PELP1 antibody, Pelp1 antibody, pelp1.L antibody
- 背景
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Background: Coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence-specific transcription factors. Plays a role in estrogen receptor (ER) genomic activity when present in the nuclear compartment by activating the ER target genes in a hormonal stimulation dependent manner. Can facilitate ER non-genomic signaling via SRC and PI3K interaction in the cytosol. Plays a role in E2-mediated cell cycle progression by interacting with RB1. May have important functional implications in ER/growth factor cross-talk. Interacts with several growth factor signaling components including EGFR and HRS. Involved in nuclear receptor signaling via its interaction with AR and NR3C1. May promote tumorigenesis via its interaction with and modulation of several oncogenes including SRC, PI3K, STAT3 and EGFR. Plays a role in cancer cell metastasis via its ability to modulate E2-mediated cytoskeleton changes and cell migration via its interaction with SRC and PI3K. Functions as the key stabilizing component of the Five Friends of Methylated CHTOP (5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Aliases: Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor) (Transcription factor HMX3), PELP1, HMX3 MNAR
- UniProt
- Q8IZL8
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