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Recombinant MGMT 抗体

MGMT 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 10G7 unconjugated Recombinant Antibody
产品编号 ABIN7127619
发货至: 中国
  • 抗原 See all MGMT 抗体
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    抗体类型
    Recombinant Antibody
    适用
    • 71
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    宿主
    • 68
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    克隆类型
    • 62
    • 16
    单克隆
    标记
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    • 3
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    This MGMT antibody is un-conjugated
    应用范围
    • 53
    • 32
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human MGMT
    克隆位点
    10G7
    亚型
    IgG
    Top Product
    Discover our top product MGMT Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    别名
    MGMT (MGMT 产品)
    别名
    AGT antibody, AI267024 antibody, Agat antibody, O-6-methylguanine-DNA methyltransferase antibody, MGMT antibody, Mgmt antibody
    背景

    Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

    Aliases: Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase), MGMT

    UniProt
    P16455
    途径
    DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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