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Recombinant Lamin A/C 抗体

LMNA 适用: 人 IHC, ELISA, IF, IP, FACS 宿主: 兔 Monoclonal 4H7 unconjugated Recombinant Antibody
产品编号 ABIN7127601
发货至: 中国
  • 抗原 See all Lamin A/C (LMNA) 抗体
    Lamin A/C (LMNA)
    抗体类型
    Recombinant Antibody
    适用
    • 131
    • 73
    • 71
    • 27
    • 15
    • 13
    • 8
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 96
    • 45
    • 2
    • 1
    克隆类型
    • 96
    • 48
    单克隆
    标记
    • 113
    • 9
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    This Lamin A/C antibody is un-conjugated
    应用范围
    • 120
    • 54
    • 53
    • 47
    • 31
    • 31
    • 30
    • 19
    • 15
    • 7
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human LMNA
    克隆位点
    4H7
    亚型
    IgG
    Top Product
    Discover our top product LMNA Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Lamin A/C (LMNA)
    别名
    LMNA (LMNA 产品)
    背景

    Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation (PubMed:10080180, PubMed:22431096, PubMed:10814726, PubMed:11799477, PubMed:18551513). Required for osteoblastogenesis and bone formation (PubMed:12075506, PubMed:15317753, PubMed:18611980). Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone (PubMed:10587585). Required for cardiac homeostasis (PubMed:10580070, PubMed:12927431, PubMed:18611980, PubMed:23666920).

    Aliases: Prelamin-A/C, Lamin-A/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1

    UniProt
    P02545
    途径
    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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