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Recombinant LGR5 抗体

LGR5 适用: 人 WB, FACS, ELISA 宿主: 兔 Monoclonal 4H8 unconjugated Recombinant Antibody
产品编号 ABIN7127600
发货至: 中国
  • 抗原 See all LGR5 抗体
    LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
    抗体类型
    Recombinant Antibody
    适用
    • 98
    • 57
    • 49
    • 1
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    宿主
    • 86
    • 13
    克隆类型
    • 78
    • 21
    单克隆
    标记
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    This LGR5 antibody is un-conjugated
    应用范围
    • 71
    • 37
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    Western Blotting (WB), Flow Cytometry (FACS), ELISA
    交叉反应
    人, 大鼠
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human LGR5/GPR49
    克隆位点
    4H8
    亚型
    IgG
    Top Product
    Discover our top product LGR5 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, FC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
    别名
    LGR5 (LGR5 产品)
    别名
    lgr5-a antibody, lgr5a antibody, FEX antibody, Gpr49 antibody, GPR49 antibody, GPR67 antibody, GRP49 antibody, HG38 antibody, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog antibody, leucine rich repeat containing G protein coupled receptor 5 antibody, leucine rich repeat containing G protein-coupled receptor 5 antibody, lgr5.L antibody, Lgr5 antibody, LGR5 antibody
    背景

    Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.

    Aliases: Leucine-rich repeat-containing G-protein coupled receptor 5 (G-protein coupled receptor 49) (G-protein coupled receptor 67) (G-protein coupled receptor HG38), LGR5, GPR49 GPR67

    UniProt
    O75473
    途径
    WNT signaling
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