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Recombinant GZMB 抗体

GZMB 适用: 人 IHC, ELISA, IF 宿主: 兔 Monoclonal 6A1 unconjugated Recombinant Antibody
产品编号 ABIN7127523
发货至: 中国
  • 抗原 See all GZMB 抗体
    GZMB (Granzyme B (GZMB))
    抗体类型
    Recombinant Antibody
    适用
    • 127
    • 48
    • 24
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    • 1
    宿主
    • 81
    • 48
    • 2
    克隆类型
    • 80
    • 51
    单克隆
    标记
    • 76
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    This GZMB antibody is un-conjugated
    应用范围
    • 69
    • 41
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    • 37
    • 19
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    Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human Granzyme B
    克隆位点
    6A1
    亚型
    IgG
    Top Product
    Discover our top product GZMB Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    GZMB (Granzyme B (GZMB))
    别名
    GZMB (GZMB 产品)
    背景

    Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

    Aliases: Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E), GZMB, CGL1 CSPB CTLA1 GRB

    UniProt
    P10144
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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