Recombinant FTO 抗体
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- 抗原 See all FTO 抗体
- FTO (Fat Mass and Obesity-Associated (FTO))
- 抗体类型
- Recombinant Antibody
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This FTO antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- Affinity-chromatography
- 免疫原
- A synthesized peptide derived from human FTO
- 克隆位点
- 4G9
- 亚型
- IgG
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anti-Fat Mass and Obesity-Associated (FTO) antibody
FTO 适用: 人 WB, ELISA, IHC, IP 宿主: 小鼠 Monoclonal AG103 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 小鼠 WB, ELISA, IHC, IP 宿主: 小鼠 Monoclonal FT62-6 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) (N-Term) antibodyFTO 适用: 人, 小鼠, 大鼠, Cow, 绵羊, Pig, 马, 猴, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 人, 小鼠, 大鼠, 犬, Cow, 绵羊, 马, 灵长类 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 5-2H10 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 小鼠 Monoclonal FT86-4 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) (AA 416-505) antibodyFTO 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Fat Mass and Obesity-Associated (FTO) (N-Term) antibodyFTO 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 5-2H10 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) (AA 1-30), (N-Term) antibodyFTO 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21572 unconjugated
anti-Fat Mass and Obesity-Associated (FTO) antibodyFTO 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- FTO (Fat Mass and Obesity-Associated (FTO))
- 别名
- FTO (FTO 产品)
- 别名
- AW743446 antibody, mKIAA1752 antibody, RGD1305121 antibody, FTO, alpha-ketoglutarate dependent dioxygenase antibody, fat mass and obesity associated antibody, fat mass and obesity associated L homeolog antibody, FTO antibody, Fto antibody, fto.L antibody
- 背景
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Background: Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine (PubMed:18775698, PubMed:20376003). Specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:22002720, PubMed:26458103). Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation (PubMed:18775698, PubMed:20376003). In particular, it is involved in the regulation of thermogenesis and the control of adipocyte differentiation into brown or white fat cells (PubMed:26287746).
Aliases: Alpha-ketoglutarate-dependent dioxygenase FTO, Fat mass and obesity-associated protein, FTO, KIAA1752
- UniProt
- Q9C0B1
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