Recombinant FOXA1 抗体
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- 抗原 See all FOXA1 抗体
- FOXA1 (Forkhead Box A1 (FOXA1))
- 抗体类型
- Recombinant Antibody
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This FOXA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
- 交叉反应
- 人
- 纯化方法
- Affinity-chromatography
- 免疫原
- A synthesized peptide derived from human FOXA1
- 克隆位点
- 3B2
- 亚型
- IgG
- Top Product
- Discover our top product FOXA1 Primary Antibody
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anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibody
FOXA1 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-Forkhead Box A1 (FOXA1) (C-Term) antibodyVerified FOXA1 适用: 人, 小鼠 WB, IF, FACS, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibodyFOXA1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B1 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibodyFOXA1 适用: 人, 大鼠 WB, IHC, StM 宿主: 小鼠 Monoclonal FOXA1-1518 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibodyFOXA1 适用: 人 WB, IHC, IF, FACS, ISt, StM 宿主: 小鼠 Monoclonal FOXA1-1512 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibodyFOXA1 适用: 人, 大鼠 IHC, ISt, StM 宿主: 小鼠 Monoclonal FOXA1-1241 unconjugated
anti-Forkhead Box A1 (FOXA1) (C-Term) antibodyFOXA1 适用: 人 WB, IF, IHC (p), IP, ChIP, ICC, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibodyFOXA1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4F6 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibodyFOXA1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3C1 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibodyFOXA1 适用: 人, 大鼠 IHC, ISt, StM 宿主: 兔 Monoclonal FOXA1-2230R unconjugated Recombinant Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IP:1:200-1:1000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- FOXA1 (Forkhead Box A1 (FOXA1))
- 别名
- FOXA1 (FOXA1 产品)
- 别名
- HNF3A antibody, TCF3A antibody, Hnf-3a antibody, Hnf3a antibody, Tcf-3a antibody, Tcf3a antibody, fkd7 antibody, forkhead-7 antibody, HNF3-alpha antibody, HNF3alpha antibody, fkh2 antibody, foxa1 antibody, hnf3a antibody, tFoxA1 antibody, tcf3a antibody, xfkh2 antibody, fkh antibody, FOXA1 antibody, Ci-fkh antibody, HNF-3a antibody, forkhead box A1 antibody, forkhead box A1 S homeolog antibody, forkhead homolog antibody, forkhead box A1 L homeolog antibody, FOXA1 antibody, Foxa1 antibody, foxa1 antibody, foxa1.S antibody, fkh antibody, foxa1.L antibody
- 背景
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Background: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). Proposed to play a role in translating the epigenetic signatures into cell type-specific enhancer-driven transcriptional programs. Its differential recruitment to chromatin is dependent on distribution of histone H3 methylated at 'Lys-5' (H3K4me2) in estrogen-regulated genes. Involved in the development of multiple endoderm-derived organ systems such as liver, pancreas, lung and prostate, FOXA1 and FOXA2 seem to have at least in part redundant roles (By similarity). Modulates the transcriptional activity of nuclear hormone receptors. Is involved in ESR1-mediated transcription, required for ESR1 binding to the NKX2-1 promoter in breast cancer cells, binds to the RPRM promoter and is required for the estrogen-induced repression of RPRM. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis.
Aliases: Hepatocyte nuclear factor 3-alpha (HNF-3-alpha) (HNF-3A) (Forkhead box protein A1) (Transcription factor 3A) (TCF-3A), FOXA1, HNF3A TCF3A
- UniProt
- P55317
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis
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