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Recombinant c-FOS 抗体

c-Fos 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Monoclonal 14C10 unconjugated Recombinant Antibody
产品编号 ABIN7127496
发货至: 中国
  • 抗原 See all c-FOS (c-Fos) 抗体
    c-FOS (c-Fos) (c-Fos)
    抗体类型
    Recombinant Antibody
    适用
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    宿主
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    克隆类型
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    单克隆
    标记
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    This c-FOS antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    交叉反应
    人, 小鼠
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human FOS
    克隆位点
    14C10
    亚型
    IgG
    Top Product
    Discover our top product c-Fos Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    c-FOS (c-Fos) (c-Fos)
    别名
    FOS (c-Fos 产品)
    别名
    AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody
    背景

    Background: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

    Aliases: Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7, FOS, G0S7

    UniProt
    P01100
    途径
    S100 Proteins
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