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Recombinant EIF2C3 抗体

EIF2C3 适用: 人 ELISA 宿主: 兔 Monoclonal 4F7 unconjugated Recombinant Antibody
产品编号 ABIN7127326
发货至: 中国
  • 抗原 See all EIF2C3 抗体
    EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))
    抗体类型
    Recombinant Antibody
    适用
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    宿主
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    克隆类型
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    单克隆
    标记
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    This EIF2C3 antibody is un-conjugated
    应用范围
    • 25
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    ELISA
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human AGO3
    克隆位点
    4F7
    亚型
    IgG
    Top Product
    Discover our top product EIF2C3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))
    别名
    AGO3 (EIF2C3 产品)
    别名
    EIF2C3 antibody, Eif2c3 antibody, Argonaute3 antibody, ago3 antibody, eif2c3 antibody, eif2c3b antibody, si:dkey-3n22.3 antibody, AW048688 antibody, C130014L07Rik antibody, ARGONAUTE 3 antibody, T19E23.8 antibody, T19E23_8 antibody, argonaute 3, RISC catalytic component antibody, argonaute RISC catalytic component 3b antibody, argonaute RISC catalytic subunit 3 antibody, argonaute RISC catalytic component 3 antibody, ARGONAUTE 3 antibody, AGO3 antibody, Ago3 antibody, ago3b antibody
    背景

    Background: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (PubMed:29040713).

    Aliases: Protein argonaute-3UniRule annotation, Argonaute RISC catalytic component 3, Eukaryotic translation initiation factor 2C 3UniRule annotation, AGO3, EIF2C3

    UniProt
    Q9H9G7
    途径
    Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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