Recombinant Histone H3.3 抗体
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- 抗原 See all Histone H3.3 (H3F3A) 抗体
- Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))
- 抗体类型
- Recombinant Antibody
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This Histone H3.3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- Affinity-chromatography
- 免疫原
- A synthesized peptide
- 克隆位点
- 4H2
- 亚型
- IgG
- Top Product
- Discover our top product H3F3A Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:50-1:500, IF:1:30-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))
- 别名
- H3F3A (H3F3A 产品)
- 背景
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Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Aliases: Histone H3.3, H3F3A, H3.3A, H3F3, PP781, AND, H3F3B, H3.3B
- UniProt
- P84243
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