电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MED21 抗体

MED21 适用: 人 WB, ELISA, IF, Coat, FACS, IP 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7127181
发货至: 中国
  • 抗原 See all MED21 抗体
    MED21 (Mediator Complex Subunit 21 (MED21))
    适用
    • 23
    • 16
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 18
    • 5
    小鼠
    克隆类型
    • 19
    • 4
    单克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MED21 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Coating (Coat), Flow Cytometry (FACS), Immunoprecipitation (IP)
    特异性
    In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase. These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors. Med6 and Med7, as well as other components of SMCC, associate with co-activator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation. Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human MED21 protein
    亚型
    IgG1
    Top Product
    Discover our top product MED21 Primary Antibody
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or K562 cells.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    MED21 (Mediator Complex Subunit 21 (MED21))
    别名
    MED21 (MED21 产品)
    别名
    SURB7 antibody, fk48d02 antibody, surb7 antibody, wu:fk48d02 antibody, zgc:56532 antibody, SRB7 antibody, hSrb7 antibody, 0610007L03Rik antibody, AI449604 antibody, D19234 antibody, D6Ertd782e antibody, Srb7 antibody, Surb7 antibody, T4B21.8 antibody, T4B21_8 antibody, mediator 21 antibody, mediator complex subunit 21 antibody, Med21p antibody, mediator 21 antibody, MED21 antibody, med21 antibody, Med21 antibody
    背景
    Forkhead box protein Q1, MED21, Hepatocyte nuclear factor 3 forkhead homolog 1, HFH1, HNF3/forkhead like protein 1, MGC77469, Q1, Winged helix / forkhead transcription factor, zgc:77469,MED21 / SRB7
    Cellular localisation: Nucleus. Nucleoplasm. Cytoplasm.
    分子量
    15.5kDa
    基因ID
    9412, 286145
    UniProt
    Q13503
    途径
    Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
You are here:
客服