ZNF408 抗体
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- 抗原 See all ZNF408 抗体
- ZNF408 (Zinc Finger Protein 408 (ZNF408))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ZNF408 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 特异性
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the Kr ppel C2H2-type zinc-finger protein family, ZNF396 (zinc finger protein 396), also known as PRDM17 (PR domain zinc finger protein 17), is a 720 amino acid nuclear protein that contains ten C2H2-type zinc fingers. The gene encoding ZNF408 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human ZNF408 protein
- 亚型
- IgG2b
- Top Product
- Discover our top product ZNF408 Primary Antibody
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or Raji cells. Ubiquitious nuclear expression.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- ZNF408 (Zinc Finger Protein 408 (ZNF408))
- 别名
- ZNF408 (ZNF408 产品)
- 别名
- Gm1011 antibody, zinc finger protein 408 antibody, ZNF408 antibody, Zfp408 antibody, Znf408 antibody, znf408 antibody
- 背景
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EVR6, PFM14, PR domain zinc finger protein 17 (PRDM17), RP72, Zinc finger protein 408 (ZNF408),ZNF408 / PRDM17 (Transcription Factor)
Cellular localisation: Nucleus. - 分子量
- 118kDa
- 基因ID
- 79797, 60300
- UniProt
- Q9H9D4
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