GTF2H2C 抗体
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- 抗原 See all GTF2H2C 抗体
- GTF2H2C (General Transcription Factor IIH, Polypeptide 2C (GTF2H2C))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GTF2H2C antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
- 交叉反应 （详细）
- Human. Predicted to react in Mouse and Rat.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human GTF2H2C protein
- 亚型
- IgG2
- Top Product
- Discover our top product GTF2H2C Primary Antibody
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anti-General Transcription Factor IIH, Polypeptide 2C (GTF2H2C) (AA 1-260) antibody
GTF2H2C 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor IIH, Polypeptide 2C (GTF2H2C) antibodyGTF2H2C 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor IIH, Polypeptide 2C (GTF2H2C) (AA 314-343), (C-Term) antibodyGTF2H2C 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB29520 unconjugated
anti-General Transcription Factor IIH, Polypeptide 2C (GTF2H2C) (AA 321-351), (C-Term) antibodyGTF2H2C 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or Raji cells. Human breast or prostate carcinoma.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- GTF2H2C (General Transcription Factor IIH, Polypeptide 2C (GTF2H2C))
- 别名
- GTF2H2C (GTF2H2C 产品)
- 别名
- GTF2H2 family member C antibody, GTF2H2C antibody
- 背景
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EVR6, PFM14, PR domain zinc finger protein 17 (PRDM17), RP72, Zinc finger protein 408 (GTF2H2C),GTF2H2C (Transcription Factor)
Cellular localisation: Nucleus. Nuclear speckles. - 分子量
- 44kDa
- 基因ID
- 730394, 422901
- UniProt
- Q6P1K8
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