SCXA 抗体
SCXA
适用: 人
FACS, IF
宿主: 小鼠
Monoclonal
unconjugated
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- 抗原 See all SCXA 抗体
- SCXA (Scleraxis (SCXA))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SCXA antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF)
- 特异性
- Transcription factors are proteins that bind DNA adjacent to genes and control the production of mRNA transcripts. Scleraxis (basic helix-loop-helix transcription factor scleraxis) is a 201 amino acid protein that dimerizes with another bHLH protein to initiate transcription. Scleraxis is known to play a role in formation of mesoderm and somite-derived chondrogenic lineages. Scleraxis localizes to the nucleus and contains one bHLH domain. bHLH transcription factors, in general, function in cellular differentiation, proliferation, and oncogene regulation. The gene encoding Scleraxis maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human SCXA protein
- 亚型
- IgG2a
- Top Product
- Discover our top product SCXA Primary Antibody
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anti-Scleraxis (SCXA) (AA 172-201), (C-Term) antibody
SCXA 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB30107 unconjugated
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or HepG2 cells.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- SCXA (Scleraxis (SCXA))
- 别名
- SCX (SCXA 产品)
- 别名
- BB114693 antibody, Bhlha41 antibody, Scl antibody, SCX antibody, bHLHa48 antibody, scleraxis antibody, scleraxis bHLH transcription factor antibody, Scx antibody, SCX antibody
- 背景
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Basic helix loop helix transcription factor scleraxis, bHLHa41, bHLHa48, Class A basic helix-loop-helix protein 41, Class A basic helix-loop-helix protein 48, scleraxis homolog A, SCX, SCXB,SCXA
Cellular localisation: Nucleus. - 分子量
- 22kDa
- 基因ID
- 642658, 723088
- UniProt
- Q7RTU7
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