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Recombinant RPSA/Laminin Receptor 抗体

RPSA 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated Recombinant Antibody
产品编号 ABIN7126636
发货至: 中国
  • 抗原 See all RPSA/Laminin Receptor (RPSA) 抗体
    RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
    抗体类型
    Recombinant Antibody
    适用
    • 52
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    宿主
    • 43
    • 10
    小鼠
    克隆类型
    • 34
    • 18
    单克隆
    标记
    • 33
    • 4
    • 2
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    This RPSA/Laminin Receptor antibody is un-conjugated
    应用范围
    • 33
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    • 4
    • 2
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    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human RPSA protein
    亚型
    IgG1
    Top Product
    Discover our top product RPSA Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: MCF-7, MDA-MB-453or HEK293 cells.Human breast, colon or ovarian carcinoma.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
    别名
    RPSA (RPSA 产品)
    别名
    37LRP antibody, 67LR antibody, LBP/p40 antibody, LRP/LR antibody, LamR antibody, rpsa antibody, LamR1 antibody, RPSA antibody, LAMBR antibody, LAMR1 antibody, LBP antibody, LRP antibody, NEM/1CHD4 antibody, SA antibody, lamR antibody, p40 antibody, 67kDa antibody, 67lr antibody, AL022858 antibody, Lamr antibody, Lamr1 antibody, Lamrl1 antibody, MLR antibody, P40 antibody, P40-3 antibody, P40-8 antibody, lamr1 antibody, zgc:55831 antibody, zgc:77824 antibody, DMRT1 antibody, 40S ribosomal protein SA antibody, 67kD laminin receptor antibody, ribosomal protein SA antibody, rssa antibody, rpsa antibody, RPSA antibody, Rpsa antibody, LOC100144340 antibody
    背景
    34/67 kDa Laminin Receptor, 37 kDa Laminin Receptor precursor, 37/67 kDa Laminin Receptor, 37LRP, 40S Ribosomal Protein SA, 67 kDa Laminin Receptor, 67LR, Colon Carcinoma Laminin-binding Protein, LAMBR, Laminin receptor 1, Laminin-binding Protein precursor p40, LAMR1, LBP/p40, LRP/LR, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, Ribosomal Protein SA (RPSA),Laminin Receptor/ RPSA (Marker of Metastatic Potential)
    Cellular localisation: Cell Surface,Cytoplasmic and Nuclear
    分子量
    37-67kDa
    基因ID
    3921, 449909
    UniProt
    P08865
    途径
    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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