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IL-15 抗体

IL15 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126581
发货至: 中国
  • 抗原 See all IL-15 (IL15) 抗体
    IL-15 (IL15) (Interleukin 15 (IL15))
    适用
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    宿主
    • 74
    • 19
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    小鼠
    克隆类型
    • 83
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    单克隆
    标记
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    This IL-15 antibody is un-conjugated
    应用范围
    • 76
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    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Interleukin-15 (IL-15), also designated IL-T, is a cloned cytokine which shares several biological activities but no sequence homology with IL-2. Human, mouse and simian IL-15 cDNA clones have been isolated and characterized. All 3 species encode a 162 amino acid residue precursor protein containing a 48 amino acid leader that is cleaved to generate the mature form of IL-15. IL-15 stimulates the proliferation of T cells and NK cells, while enhancing B cell expansion and antibody production. Unlike IL-2, IL-15 is not produced by lymphocytes, but appears to be produced by macrophages, epithelial lines, muscle and placenta. IL-15 has also been shown to be a chemoattractant for human blood T lymphocytes and to be able to induce lymphokine-activated killer (LAK) activity in NK cells as well as to be able to induce the generation of cytolytic effector cells. Studies have shown that IL-15 is the only other cytokine that shares the i² signaling subunit of the IL-2R. Evidence also suggests that like IL-2, IL-4 and IL-7, IL-15 utilizes the common IL-2Ri³ subunit.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment of human IL15(exact sequence is proprietary)
    亚型
    IgG1
    Top Product
    Discover our top product IL15 Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human placenta,skeletal muscle or adrenal gland.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    IL-15 (IL15) (Interleukin 15 (IL15))
    别名
    IL15 (IL15 产品)
    别名
    IL15 antibody, AI503618 antibody, IL-15 antibody, interleukin 15 antibody, IL15 antibody, Il15 antibody
    背景
    Interleukin-15 (IL-15), MGC9721,Interleukin-15 (IL-15)
    Cellular localisation: Secreted. Cytoplasm. Nuclear.
    分子量
    14-15kDa
    基因ID
    3600, 654378
    途径
    JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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