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TOX3 抗体 (AA 251-389)

TOX3 适用: 人 WB, ELISA, IHC, Coat 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126479
发货至: 中国
  • 抗原 See all TOX3 抗体
    TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))
    抗原表位
    • 22
    • 7
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    AA 251-389
    适用
    • 46
    • 8
    宿主
    • 25
    • 20
    • 1
    小鼠
    克隆类型
    • 25
    • 21
    单克隆
    标记
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TOX3 antibody is un-conjugated
    应用范围
    • 32
    • 30
    • 21
    • 20
    • 17
    • 7
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Coating (Coat)
    特异性
    It recognizes a 63 kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment of human TOX3 protein (around aa 251-389) (Exact sequence is proprietary)
    亚型
    IgG2b
    Top Product
    Discover our top product TOX3 Primary Antibody
  • 应用备注

    Known_Application: ELISA (For coating, order Ab without BSA), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

    Positive_Control: A431 cell lysate (WB). Human breast or gastric carcinoma (IHC).

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))
    别名
    TOX3 (TOX3 产品)
    别名
    TNRC9 antibody, cagf9 antibody, tnrc9 antibody, CAGF9 antibody, 500-9 antibody, BC052044 antibody, C230068E13 antibody, Tnrc9 antibody, TOX high mobility group box family member 3 antibody, TOX3 antibody, tox3 antibody, Tox3 antibody
    背景
    TOX3, CAG trinucleotide repeat-containing gene F9 protein, CAGF9, TOX high mobility group box family member 3, Trinucleotide repeat containing 9 (TNRC9),TOX3 / TNRC9
    Cellular localisation: Cytoplasmic & Nuclear
    分子量
    63kDa
    基因ID
    27324, 460789
    UniProt
    O15405
    途径
    Chromatin Binding
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