Kallikrein 5 抗体 (AA 36-177)
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- 抗原 See all Kallikrein 5 (KLK5) 抗体
- Kallikrein 5 (KLK5)
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抗原表位
- AA 36-177
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Kallikrein 5 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Human pancreatic/renal KLK encodes for the KLK1 enzyme, which is involved in post-translational processing of polypeptide precursors. The function of the other members of KLK gene family is still currently unknown, but evidence suggests that many KLKs are implicated in carcinogenesis. The human KLK gene family consists of 15 serine proteases. The human KLK genes are clustered on chromosome 19q13. Unlike other kalllikreins, the KLK4-15 encoded proteases are less related and do not contain a conventional KLK loop. Clusters of genes exhibit high prostatic (KLK2-4, KLK15) or pancreatic (KLK6-13) expression. KLK2 is also known as glandular kallikrein 2, tissue kallikrein, or HGK-1 and KLK3 is known as prostate-specific antigen (PSA). Both KLK2 and KLK3 have important applications in prostate cancer and breast cancer diagnostics. Many of the KLKs are regulated by steroid hormones and a few of them, specifically KLK3, KLK6 and KLK10, are known to be downregulated in breast and other cancers. KLK5 expression is abundant in skin, mammary gland and testis.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment of human KLK5 protein (around aa 36-177) (exact sequence is proprietary)
- 亚型
- IgG2
- Top Product
- Discover our top product KLK5 Primary Antibody
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anti-Kallikrein 5 (KLK5) (AA 25-261) antibody
KLK5 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 5 (KLK5) (AA 23-293) antibodyKLK5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 5 (KLK5) antibodyKLK5 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 5 (KLK5) antibodyKLK5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 5 (KLK5) (Internal Region) antibodyVerified KLK5 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Kallikrein 5 (KLK5) (AA 144-174) antibodyKLK5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB6112 unconjugated
anti-Kallikrein 5 (KLK5) (AA 1-293) antibodyKLK5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Kallikrein 5 (KLK5) (AA 194-293) antibodyKLK5 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3H3 unconjugated
anti-Kallikrein 5 (KLK5) (AA 35-84) antibodyKLK5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 5 (KLK5) (C-Term) antibodyKLK5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human skin tissue (IHC).
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- Kallikrein 5 (KLK5)
- 别名
- KLK5 (KLK5 产品)
- 背景
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HK5, Kallikrein L2, Kallikrein like protein 2, Kallikrein related peptidase 5, Kallikrein-like protein 2 (KLKL2), Stratum corneum tryptic enzyme (SCTE),Kallikrein 5 (KLK5)
Cellular localisation: Secreted - 分子量
- 33kDa
- 基因ID
- 25818, 50915
- UniProt
- Q9Y337
- 途径
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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