ZHX3 抗体
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- 抗原 See all ZHX3 抗体
- ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ZHX3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Coating (Coat), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human ZHX3 protein
- 亚型
- IgG2a
- Top Product
- Discover our top product ZHX3 Primary Antibody
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- 应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human kidney, brain or thyroid.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))
- 别名
- ZHX3 (ZHX3 产品)
- 别名
- tix1 antibody, zgc:110489 antibody, TIX1 antibody, 1810059C13Rik antibody, 4932418O04Rik antibody, 9530010N21Rik antibody, Tix1 antibody, mKIAA0395 antibody, zinc fingers and homeoboxes 3 antibody, zhx3 antibody, ZHX3 antibody, Zhx3 antibody
- 背景
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KIAA0395, TIX1, Triple homeobox protein 1, ZHX 3, Zhx3, Zinc finger and homeodomain protein 3, Zinc fingers and homeoboxes protein 3,ZHX3 (Transcriptional Repressor)
Cellular localisation: Nucleus. - 分子量
- 105kDa
- 基因ID
- 23051, 380133
- UniProt
- Q9H4I2
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