JAZF1 抗体 (AA 1-130)
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- 抗原 See all JAZF1 抗体
- JAZF1 (JAZF Zinc Finger 1 (JAZF1))
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抗原表位
- AA 1-130
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This JAZF1 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP)
- 特异性
- JAZF1 (juxtaposed with another zinc finger protein 1), also known as TIP27 (TAK1-interacting protein 27) or ZNF802 (zinc finger protein 802), is a 243 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Existing as multiple alternatively spliced isoforms, JAZF1 interacts with the nuclear orphan receptor TR4 and is thought to function as a transcriptional repressor, effectively down-regulation the expression of TR4. Chromosomal aberrations in the gene encoding JAZF1 are associated with the pathogenesis of endometrial stromal tumors, suggesting a role for JAZF1 in carcinogenesis.
- 交叉反应 (详细)
- Human. Predicted to react in Mouse.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment (around aa1-130) of human JAZF1 protein (exact sequence is proprietary)
- 亚型
- IgG2a
- Top Product
- Discover our top product JAZF1 Primary Antibody
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- 应用备注
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Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or U87 cells. Ubiquitous tissue expression.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- JAZF1 (JAZF Zinc Finger 1 (JAZF1))
- 别名
- JAZF1 (JAZF1 产品)
- 别名
- TIP27 antibody, ZNF802 antibody, JAZF1 antibody, AI591476 antibody, C820002C15 antibody, Jaz1 antibody, Tip27 antibody, zgc:103778 antibody, JAZF zinc finger 1 antibody, JAZF zinc finger 1b antibody, JAZF1 antibody, Jazf1 antibody, jazf1b antibody
- 背景
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DKFZp761K2222, TIP27, ZNF802,JAZF1 (Transcription Corepressor)
Cellular localisation: Nucleus. - 分子量
- 27.08kDa
- 基因ID
- 221895, 368944
- UniProt
- Q86VZ6
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