Reelin 抗体 (AA 1796-2115)
Quick Overview for Reelin 抗体 (AA 1796-2115) (ABIN7126322)
抗原
See all Reelin (RELN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1796-2115
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特异性
- Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.
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交叉反应 （详细）
- Human, Mouse and Rodent.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa 1796-2115) of human RELN protein
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亚型
- IgG2b
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anti-Reelin (RELN) (AA 3143-3461) antibody
RELN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Reelin (RELN) (N-Term) antibodyRELN 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Reelin (RELN) (AA 26-190) antibodyRELN 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Reelin (RELN) (AA 2978-3373) antibodyRELN 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Reelin (RELN) (AA 26-254) antibodyRELN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Reelin (RELN) antibodyMicroarray verified RELN 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB299520 unconjugated
anti-Reelin (RELN) (AA 3142-3460) antibodyRELN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Reelin (RELN) (AA 2086-2296) antibodyRELN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Reelin (RELN) (AA 26-190) antibodyRELN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Reelin (RELN) (AA 2400-2610) antibodyRELN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human or mouse brain or CNS.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Reelin (RELN)
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别名
- RELN
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背景
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LIS2, PRO1598, Reeler, Reelin, RELN, RELN_HUMAN, RL,Reelin
Cellular localisation: Cytoplasm -
分子量
- 387.5kDa
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基因ID
- 19699, 655654
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UniProt
- P78509
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途径
- Synaptic Membrane
抗原
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