DMRT2 抗体
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- 抗原 See all DMRT2 抗体
- DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DMRT2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 特异性
- The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human DMRT2 protein
- 亚型
- IgG2b
- Top Product
- Discover our top product DMRT2 Primary Antibody
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or MCF-7 cells.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))
- 别名
- DMRT2 (DMRT2 产品)
- 别名
- dmrt2 antibody, zDmrt2 antibody, Terra antibody, DMRT2 antibody, dmrt2a antibody, MGC131063 antibody, Terra-like antibody, Ci-DMRT2 antibody, doublesex and mab-3 related transcription factor 2 antibody, doublesex and mab-3 related transcription factor 2a antibody, doublesex and mab-3 related transcription factor 2 L homeolog antibody, doublesex and mab-3 related transcription factor 2b antibody, DMRT2 antibody, dmrt2a antibody, Dmrt2 antibody, dmrt2 antibody, dmrt2.L antibody, LOC778577 antibody, dmrt2b antibody
- 背景
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Doublesex and mab-3 related transcription factor 2, doublesex-like 2 protein (DSXL-2), terra like protein antibody,DMRT2 (Transcription Factor)
Cellular localisation: Nucleus - 分子量
- 62kDa
- 基因ID
- 10655, 59506
- UniProt
- Q9Y5R5
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