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Recombinant Podoplanin 抗体 (AA 1-100)

PDPN 适用: Synthetic ELISA, IF, Coat, IHC (f) 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
产品编号 ABIN7504147
发货至: 中国
  • 抗原 See all Podoplanin (PDPN) 抗体
    Podoplanin (PDPN)
    抗体类型
    Recombinant Antibody
    抗原表位
    • 12
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    适用
    • 82
    • 25
    • 6
    • 3
    Synthetic
    宿主
    • 56
    • 29
    • 6
    • 6
    • 2
    • 2
    • 1
    克隆类型
    • 54
    • 48
    单克隆
    标记
    • 62
    • 11
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Podoplanin antibody is un-conjugated
    应用范围
    • 77
    • 38
    • 30
    • 26
    • 22
    • 17
    • 15
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (IF), Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    It recognizes a muco-protein of 38-43 kDa, which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endotheliumas well as lymphoangiomas,Kaposi sarcomas,and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.
    交叉反应 (详细)
    Human.
    纯化方法
    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
    免疫原
    Synthetic peptide corresponding to residues within aa1-100 of Podoplanin
    亚型
    IgG
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  • 应用备注

    Positive Control: Human tonsil, cervical or lung carcinoma tissues.

    Known Application: ELISA (For coating, order antibody without BSA), Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
    有效期
    24 months
  • 抗原
    Podoplanin (PDPN)
    别名
    PDPN (PDPN 产品)
    背景
    Aggrus, Glycoprotein 36 KD, Glycoprotein 36, gp36, GP38, GP40, HT1A1, hT1alpha1, hT1alpha2, Lung type I cell membrane associated glycoprotein, Lung type I cell membrane associated glycoprotein T1A 2, OTS8,Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker)
    Cellular localisation: Cell Surface
    分子量
    17kDa
    基因ID
    10630, 468675
    UniProt
    Q86YL7
    途径
    Dicarboxylic Acid Transport
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