Recombinant CDX2 抗体
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- 抗原 See all CDX2 抗体
- CDX2 (Caudal Type Homeobox 2 (CDX2))
- 抗体类型
- Recombinant Antibody
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适用
- 人, Synthetic
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This CDX2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
- 免疫原
- Recombinant fragments and synthetic peptides from human CDX2 protein (exact sequences are proprietary)
- 亚型
- IgG
- Top Product
- Discover our top product CDX2 Primary Antibody
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- 应用备注
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Positive Control: HT29 cells. Human colon carcinoma
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
- 有效期
- 24 months
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- 抗原
- CDX2 (Caudal Type Homeobox 2 (CDX2))
- 别名
- CDX2 (CDX2 产品)
- 别名
- CDX2 antibody, MGC130987 antibody, cdx3-like antibody, CDX-3 antibody, CDX3 antibody, CDX-2 antibody, Cdx-2 antibody, caudal type homeobox 2 antibody, caudal type homeobox 2 L homeolog antibody, caudal type homeo box 2 antibody, CDX2 antibody, cdx2.L antibody, Cdx2 antibody
- 背景
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Caudal type homeobox 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX2,CDX2 / Caudal Type Homeobox 2 (GI Epithelial Marker)
Cellular localisation: Nuclear - 分子量
- 40kDa
- 基因ID
- 1045, 174249
- UniProt
- Q99626
- 途径
- Peptide Hormone Metabolism, Stem Cell Maintenance
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