TOM1L1 抗体
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- 抗原 See all TOM1L1 抗体
- TOM1L1 (Target of Myb1 (Chicken)-Like 1 (TOM1L1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TOM1L1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Tom1 (target of Myb 1) is a 492 amino acid cytoplasmic protein that belongs to the Tom1 family. Widely expressed with highest expression in heart, liver, placenta and skeletal muscle, Tom1 is thought to be involved in intracellular trafficking and may be associated with the translocation of ubiquitinated proteins to early endosomes for degradation. Tom1 contains one GAT domain and one VHS domain through which it interacts and complexes with proteins such as Tollip and endofin (also known as SARA). These interactions recruit Tom1 to the endosome, allowing it to participate in the endosomal trafficking of ubiquitin-tagged proteins.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
- 免疫原
- Recombinant full-length human TOM1L1 protein
- 亚型
- IgG
- Top Product
- Discover our top product TOM1L1 Primary Antibody
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- 应用备注
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Positive Control: Human kidney.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
- 有效期
- 24 months
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- 抗原
- TOM1L1 (Target of Myb1 (Chicken)-Like 1 (TOM1L1))
- 别名
- TOM1L1 (TOM1L1 产品)
- 别名
- MGC52738 antibody, srcasm antibody, TOM1L1 antibody, OK/KNS-CL.3 antibody, SRCASM antibody, RGD1562626 antibody, Srcasm antibody, 2310045L10Rik antibody, C80573 antibody, target of myb1 like 1 membrane trafficking protein L homeolog antibody, target of myb1 like 1 membrane trafficking protein antibody, target of myb1-like 1 (chicken) antibody, tom1l1.L antibody, TOM1L1 antibody, tom1l1 antibody, Tom1l1 antibody
- 背景
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2310045L10Rik, C80573, OK/KNS CL.3, Src activating and signaling molecule, SRCASM, Target of Myb like protein 1, Target of myb1 (chicken) homolog like 1, Target of myb1 (chicken) like 1, TOM1 like protein 1, TOM1L1 protein,TOM1L1 (Target of Myb1 Like 1 Membrane Trafficking Protein)
Cellular localisation: Golgi apparatus > Golgi stack. Endosome membrane. - 分子量
- 53kDa.
- 基因ID
- 10040, 153504
- UniProt
- O75674
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