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MEF2B 抗体

MEF2B 适用: 人 WB, IF, FACS, IP 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7504178
发货至: 中国
  • 抗原 See all MEF2B 抗体
    MEF2B (Myocyte Enhancer Factor 2B (MEF2B))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This MEF2B antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)
    特异性
    The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.
    交叉反应 (详细)
    Human.
    纯化方法
    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
    免疫原
    Recombinant full-length human MEF2B protein
    亚型
    IgG2a
  • 应用备注

    Positive Control: HeLa or Ramos cells.

    Known Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein), Western Blot (1-2 μg/mL),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
    有效期
    24 months
  • 抗原
    MEF2B (Myocyte Enhancer Factor 2B (MEF2B))
    别名
    MEF2B (MEF2B 产品)
    别名
    si:ch211-125m10.1 antibody, AI451606 antibody, RSRFR2 antibody, myocyte enhancer factor 2b antibody, myocyte enhancer factor 2B antibody, mef2b antibody, MEF2B antibody, Mef2b antibody
    背景
    MADS box transcription enhancer factor 2, MDS1 EVI1, Mef2b, Myocyte enhancer factor 2B, Myocyte-specific enhancer factor 2B, PRDM3, RSRFR2, Serum response factor like protein 2, XMEF2,MEF2B (Transcriptional Activator)
    Cellular localisation: Nucleus.
    分子量
    160kDa
    基因ID
    100271849, 4207, 153629
    UniProt
    Q02080
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