ZNF238 抗体
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- 抗原 See all ZNF238 抗体
- ZNF238 (Zinc Finger Protein 238 (ZNF238))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZNF238 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- zinc finger protein 238
- 亚型
- IgG
- Top Product
- Discover our top product ZNF238 Primary Antibody
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- 应用备注
- WB: 1:500-1:5000, IP: 1:500-1:5000, IHC: 1:20-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- ZNF238 (Zinc Finger Protein 238 (ZNF238))
- 别名
- ZNF238 (ZNF238 产品)
- 别名
- si:ch211-221n23.1 antibody, znf238 antibody, C2H2-171 antibody, RP58 antibody, TAZ-1 antibody, ZNF238 antibody, Zfp238 antibody, Znf238 antibody, Rp58 antibody, Zbtb18 antibody, zinc finger and BTB domain containing 18 antibody, zinc finger and BTB domain containing 18 L homeolog antibody, zbtb18 antibody, zbtb18.L antibody, ZBTB18 antibody, Zbtb18 antibody
- 背景
- Synonyms:58 kDa repressor protein, C2H2 171, RP58, TAZ 1, TAZ1, Transcriptional repressor RP58, ZBTB18, ZFP238, zinc finger protein 238, Zinc finger protein C2H2 171, ZNF238 Background:ZNF238 is a member of the BTB/POZ-ZF protein family, which involve in development and cancer formation, for example BCL-6, PLZF, and HIC-1. It's a transcriptional repressor involve in myogenesis and brain development. By directly repressing the expression of two skeletal myogenesis inhibitors, ID2 and ID3, ZNF238 plays a key role in myogenesis. It can control cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Besides, ZNF238 involves in the organization of nuclear chromosomes, for its specific binding to the consensus DNA sequence that contains the E box core, and recruiting chromatin remodeling multiportein complex. ZNF238 proteins has apparent molecular masses of 60 and 48 kD. Specific binding is found for a 60- kDa band which corresponds to the full length of RP58 protein. In addition, a 48- kDa band, thought to be the truncated form 2 is detected(PMID: 9756912).
- 分子量
- 48 kDa
- UniProt
- Q99592
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