YTHDF2 抗体
-
- 抗原 See all YTHDF2 抗体
- YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This YTHDF2 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- YTH domain family, member 2
- 亚型
- IgG
- Top Product
- Discover our top product YTHDF2 Primary Antibody
-
anti-YTH Domain Family, Member 2 (YTHDF2) (AA 201-500) antibody
YTHDF2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-YTH Domain Family, Member 2 (YTHDF2) antibodyYTHDF2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-YTH Domain Family, Member 2 (YTHDF2) (AA 1-579) antibodyYTHDF2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
- 应用备注
- WB: 1:1000-1:10000, IF: 1:10-1:100, IP: 1:200-1:1000, IHC: 1:20-1:200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
-
- 抗原
- YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))
- 别名
- YTHDF2 (YTHDF2 产品)
- 别名
- MGC82537 antibody, HGRG8 antibody, NY-REN-2 antibody, YTH N(6)-methyladenosine RNA binding protein 2 L homeolog antibody, YTH N6-methyladenosine RNA binding protein 2 antibody, ythdf2.L antibody, YTHDF2 antibody
- 背景
- Synonyms:CLL associated antigen KW 14, HGRG8, NY REN 2, YTH domain family protein 2, YTH domain family, member 2, YTHDF2 Background:Specifically recognizes and binds N6-methyladenosine(m6A)-containing RNAs, and regulates mRNA stability(PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability(PubMed:22575960, PubMed:24284625, PubMed:25412658, PubMed:25412661). Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies(P-bodies), leading to mRNA degradation(PubMed:24284625, PubMed:26046440). Also acts as a promoter of cap-independent mRNA translation following heat shock stress: upon stress, relocalizes to the nucleus and specifically binds mRNAs with some m6A methylation mark at their 5'-UTR, protecting demethylation of mRNAs by FTO, thereby promoting cap-independent mRNA translation(PubMed:26458103).
- 分子量
- 68 kDa
- 基因ID
- 51441
- UniProt
- Q9Y5A9
-
