YTHDC1 抗体
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- 抗原 See all YTHDC1 抗体
- YTHDC1 (YTH Domain Containing 1 (YTHDC1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This YTHDC1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- YTH domain containing 1
- 亚型
- IgG
- Top Product
- Discover our top product YTHDC1 Primary Antibody
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anti-YTH Domain Containing 1 (YTHDC1) (AA 260-500) antibody
YTHDC1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-YTH Domain Containing 1 (YTHDC1) (AA 89-153) antibodyYTHDC1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-YTH Domain Containing 1 (YTHDC1) antibodyYTHDC1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-YTH Domain Containing 1 (YTHDC1) antibodyYTHDC1 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:200-1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- YTHDC1 (YTH Domain Containing 1 (YTHDC1))
- 别名
- YTHDC1 (YTHDC1 产品)
- 别名
- C80342 antibody, mKIAA1966 antibody, A730098D12Rik antibody, zgc:101592 antibody, MGC89461 antibody, MGC137509 antibody, DKFZp459L1228 antibody, YT521 antibody, YT521-B antibody, Yt521 antibody, YTH domain containing 1 antibody, YTH domain containing 1 L homeolog antibody, Ythdc1 antibody, YTHDC1 antibody, ythdc1 antibody, ythdc1.L antibody
- 背景
- Synonyms:KIAA1966, Putative splicing factor YT521, YT521, YT521 B, YTH domain containing 1, YTHDC1 Background:Regulator of alternative splicing that specifically recognizes and binds N6-methyladenosine(m6A)-containing RNAs(PubMed:26318451, PubMed:26876937, PubMed:25242552). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability(PubMed:26318451, PubMed:25242552). Acts as a key regulator of exon-inclusion or exon-skipping during alternative splicing via interaction with mRNA splicing factors SRSF3 and SRSF10(PubMed:26876937). Specifically binds m6A-containing mRNAs and promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing(PubMed:26876937). In contrast, interaction with SRSF3 prevents interaction with SRSF10, a splicing factor that promotes exon skipping: this prevents SRSF10 from binding to its mRNA-binding sites close to m6A-containing regions, leading to inhibit exon skipping during alternative splicing(PubMed:26876937). May also regulate alternative splice site selection(PubMed:20167602).
- 分子量
- 110 kDa
- 基因ID
- 91746
- UniProt
- Q96MU7
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