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WDR24 抗体

WDR24 适用: 人, 小鼠 ELISA, IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7120816
发货至: 中国
  • 抗原 See all WDR24 products
    WDR24 (WD Repeat Domain 24 (WDR24))
    适用
    人, 小鼠
    宿主
    • 7
    克隆类型
    • 7
    多克隆
    标记
    • 4
    • 1
    • 1
    • 1
    This WDR24 antibody is un-conjugated
    应用范围
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    WD repeat domain 24
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:5000, IP: 1:200-1:2000, IF: 1:10-1:100, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    WDR24 (WD Repeat Domain 24 (WDR24))
    别名
    WDR24 (WDR24 产品)
    别名
    C16orf21 antibody, JFP7 antibody, BC037651 antibody, wu:fd05f12 antibody, zgc:55946 antibody, WD repeat domain 24 antibody, WD repeat domain 24 L homeolog antibody, WDR24 antibody, Wdr24 antibody, wdr24 antibody, wdr24.L antibody
    背景
    Synonyms:C16orf21, DKFZp434F054, JFP7, WD repeat domain 24, WDR24 Background:As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2(PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux(PubMed:27166823).
    分子量
    102 kDa
    基因ID
    84219
    UniProt
    Q96S15
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